Scleroderma – Definition
Scleroderma is a rare disease of the connective tissue. It can cause the tissue in skin, joints, and internal organs to thicken and stiffen. There are three major forms of the disease:
- Localized scleroderma (also known as morphea) — usually affects only the skin in isolated parts of the body. This form is less serious.
- Systemic scleroderma — affects widespread areas of skin and/or internal organs, most often the lungs (Certain categories of this form of scleroderma are more serious and can be fatal.)
- Overlap syndrome — may involve features of scleroderma and features of other autoimmune syndromes